Cheyenne Airport Car Hire (CYS)

Cheyenne Regional Airport (CYS) serves Wyoming's capital and offers car rental through 2 rental companies for trips in southern Wyoming and north toward Casper. The airport is 6 km north of Cheyenne center and is the perfect starting point for exploring Medicine Bow National Forest and the Laramie Mountains. Denver International Airport is just 160 km to the south if you want more flight options.

Cheyenne center with Wyoming State Capitol is reached in 10 minutes south via Yellowstone Road. Laramie, the university town, is 80 km to the west via I-80 and is reached in 50 minutes. Vedauwoo Recreation Area with dramatic granite formations is 40 km west of Cheyenne, perfect for a day trip.

Cheyenne Frontier Days at the end of July is one of the world's largest rodeos – book your rental car months in advance. I-80 west toward Salt Lake City is a classic Wyoming drive with desolate views. Combine Cheyenne with a visit to Laramie and drive back via scenic byway along Highway 210 (Happy Jack Road).

How far is it from Cheyenne Airport to Denver? About 160 km south via I-25, which takes approximately 1.5–2 hours depending on traffic near Denver. Can I rent a car in Cheyenne and return it in another city?

Yes, one-way rental is possible but often comes with an extra fee. Contact the rental company for current terms. What type of car is best suited for Wyoming?

An SUV or crossover is recommended, especially if you plan to leave the highway for natural areas or travel during winter.

We compare prices from all major providers at Cheyenne Airport so you can see the total cost upfront — including insurance, fuel terms and any extras. Most bookings include free cancellation up to 48 hours before pickup, giving you flexibility if your plans change.