Rochester Airport Car Rental (RST)

Rochester International Airport (RST) is located 13 km southeast of Rochester center, approximately 15 minutes' drive via US-63 North. Four rental companies are on-site, making it easy to pick up a car immediately upon landing and drive to Mayo Clinic in under 20 minutes. The airport is the gateway to southern Minnesota's most visited city.

RST is primarily serviced by travelers to Mayo Clinic, one of the world's leading hospitals located 14 km north in the downtown area. Olmsted County with its 1,800 lakes and Whitewater State Park, 35 km east, attract nature enthusiasts who choose to rent a car to explore the area. Book a rental car in advance - capacity is limited and Mayo Clinic visitors often fill up availability.

Drive US-63 North directly into Rochester center; the route is fast and well-signposted. Check road conditions in winter - the RST area can be hit by heavy snowfall November - March. How long does it take to drive from RST to Mayo Clinic?

Approximately 15-20 minutes via US-63 North, a distance of about 14 km. Which rental companies are at Rochester Airport? There are four rental companies at RST, providing a good selection of vehicle types and prices.

Is it possible to rent a car for a one-way trip to Minneapolis? Yes, Minneapolis is 145 km north via US-52, approximately 1.5 hours' drive. One-way fees may apply.

We compare prices from all major providers at Rochester Airport so you can see the total cost upfront - including insurance, fuel terms and any extras. Most bookings include free cancellation up to 48 hours before pickup, giving you flexibility if your plans change.