Car Rental at Florence Airport (FLO)

Florence Regional Airport (FLO) serves northeastern South Carolina and is just 6 km from Florence center. With 5 rental companies on site, it's easy to pick up a rental car and hit the roads in the Pee Dee region. The airport is a practical alternative for travelers exploring Myrtle Beach or the interior of South Carolina.

Florence's center with its restaurants and shops along Evans Street is reached in 10 minutes from the airport. Myrtle Beach is 120 km to the southeast and takes approximately 1 hour and 20 minutes to drive via US-501. Francis Marion National Forest, with 100,000 hectares of woodland, begins just 60 km to the south.

Rent a mid-size car if you're planning longer excursions - the distance to Charleston is 185 km and takes about 2 hours via I-26. Avoid picking up a car during the Tobacco Festival in September when demand increases significantly. Fill up your tank in Florence before heading out to the countryside where gas stations can be far apart.

How far is it from Florence Airport to Myrtle Beach? It's approximately 120 km and takes about 1 hour and 20 minutes to drive via US-501 to the east. Which rental companies operate at Florence Regional Airport?

There are 5 rental companies at FLO, including the major chains. Compare car rental prices on SmartCarRental.com for the best deals. Can I drive to Columbia from Florence with a rental car?

Yes, Columbia is 130 km to the west via I-20 and the journey takes about 1 hour and 30 minutes.

We compare prices from all major providers at Florence Airport so you can see the total cost upfront - including insurance, fuel terms and any extras. Most bookings include free cancellation up to 48 hours before pickup, giving you flexibility if your plans change.