Car Rental in Panama City

Panama City downtown is the city's pulse with nine rental agencies concentrated along Avenida Balboa and near Via España, giving you the largest vehicle selection in the entire country. From here it's 2 km to Casco Viejo and 4 km to Punta Paitilla, perfect for exploring the neighborhoods on foot or by car. The downtown location makes it easy to jump onto Corredor Sur toward Tocumén or west toward the canal zone.

Along Avenida Balboa runs the iconic waterfront promenade with views of Panama Bay's skyline and Casco Viejo. Via España is the city's commercial backbone with banks, restaurants, and hotels such as Marriott and Sheraton. Plaza Cinco de Mayo, a historic plaza, is just 1 km from most rental offices.

Choose a hotel with parking if you rent a car downtown – street parking is limited and expensive. Never drive into Casco Viejo with a rental car during weekend evenings when roads are closed for pedestrians. Compare prices among the nine rental agencies online before you arrive.

What rental agencies are located in Panama City downtown? Downtown includes Hertz, Avis, Budget, National and several local operators – a total of nine rental agencies to choose from. How do I get from downtown to the Panama Canal?

Miraflores Locks are about 12 km to the west, approximately 20 minutes' drive via Gaillard Highway. Is it safe to park a rental car in Panama City downtown? Always use monitored parking garages, particularly at Multiplaza Pacific or the hotels' own garages, and never leave valuables visible in the car.

We compare prices from all major providers at Panama City Center so you can see the total cost upfront — including insurance, fuel terms and any extras. Most bookings include free cancellation up to 48 hours before pickup, giving you flexibility if your plans change.